AV-153 free base
Modify Date: 2024-01-02 11:46:40
AV-153 free base structure
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Common Name | AV-153 free base | ||
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| CAS Number | 19350-66-4 | Molecular Weight | 297.30400 | |
| Density | 1.23g/cm3 | Boiling Point | 450.5ºC at 760mmHg | |
| Molecular Formula | C14H19NO6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 226.3ºC | |
Use of AV-153 free baseAV-153 free base, a 1,4-dihydropyridine (1,4-DHP) derivative, is an antimutagenic. AV-153 free base intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro. AV-153 free base interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation. AV-153 free base has anti-cancer activity[1][2][3]. |
| Name | 3,5-bis(ethoxycarbonyl)-2,6-dimethyl-1,4-dihydropyridine-4-carboxylic acid |
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| Synonym | More Synonyms |
| Description | AV-153 free base, a 1,4-dihydropyridine (1,4-DHP) derivative, is an antimutagenic. AV-153 free base intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro. AV-153 free base interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation. AV-153 free base has anti-cancer activity[1][2][3]. |
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| Related Catalog | |
| In Vitro | AV-153 free base causes IC50s for Raji and HL-60 cells of 14.9 mM and 10.3 mM, respectively[1]. AV-153 free base (1 nM to 10 μM; 3 hours) reduces the level of spontaneously arising DNA single-strand breaks (SSBs) in peripheral blood lymphocytes or HL-60 cells by 13–67%[1]. |
| References |
| Density | 1.23g/cm3 |
|---|---|
| Boiling Point | 450.5ºC at 760mmHg |
| Molecular Formula | C14H19NO6 |
| Molecular Weight | 297.30400 |
| Flash Point | 226.3ºC |
| Exact Mass | 297.12100 |
| PSA | 101.93000 |
| LogP | 1.29340 |
| Vapour Pressure | 2.26E-09mmHg at 25°C |
| Index of Refraction | 1.51 |
| HS Code | 2933399090 |
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| HS Code | 2933399090 |
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| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| 2,6-Dimethyl-1,4-dihydro-pyridine-3,4,5-tricarboxylic acid 3,5-diethyl ester |
| 2.6-dimethyl-3,5-diethoxycarbonyl-1-4-dihydroisonicotinic acid |
| 3,5-Diethoxycarbonyl-2,6-dimethyl-1,4-dihydroisonicotinsaeure |
| 2,6-Dimethyl-3,5-diethoxycarbonyl-1,4-dihydro-pyridin-4-carbonsaeure |
| 3,4,5-pyridinetricarboxylic acid,1,4-dihydro-2,6-dimethyl-,3,5-diethyl ester |
| 2,5-DIISOPROPYLPHENOL |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: AV-153 free base
- Price: Click To Check
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: AV-153 free base
- Price: ￥11746.0/5g ￥4046.0/1g ￥1616.0/250mg ￥1016.0/100mg
- Purity: 97.0%
- Delivery: 1 Day
- Contact: Liu jia
- Email: 2130147988@qq.com
- DC Chemicals Limited
- China
- Product Name: AV-153 free base
- Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 2,6-DIMETHYL-1,4-DIHYDRO-PYRIDINE-3,4,5-TRICARBOXYLIC ACID 3,5-DIETHYL ESTER
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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Price: ￥1100/10 mM * 1 mL in DMSO
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