gelatinase a

Modify Date: 2024-01-14 17:51:41

gelatinase a Structure
gelatinase a structure
Common Name gelatinase a
CAS Number 193807-58-8 Molecular Weight 381.445
Density 1.3±0.1 g/cm3 Boiling Point 595.9±60.0 °C at 760 mmHg
Molecular Formula C21H19NO4S Melting Point N/A
MSDS N/A Flash Point 314.2±32.9 °C

 Use of gelatinase a


MMP-2/MMP-9-IN-1 is a highly selective, orally active and potent type IV collagenase (MMP-9 and MMP-2) inhibitor with IC50s of 0.24 and 0.31 μM for MMP-9 and MMP-2, respectively. MMP-2/MMP-9-IN-1 is orally active in animal models of tumor growth and metastasis. MMP-2/MMP-9-IN-1 can be used for the research of cancer[1].

 Names

Name N-(4-Biphenylylsulfonyl)-D-phenylalanine
Synonym More Synonyms

 gelatinase a Biological Activity

Description MMP-2/MMP-9-IN-1 is a highly selective, orally active and potent type IV collagenase (MMP-9 and MMP-2) inhibitor with IC50s of 0.24 and 0.31 μM for MMP-9 and MMP-2, respectively. MMP-2/MMP-9-IN-1 is orally active in animal models of tumor growth and metastasis. MMP-2/MMP-9-IN-1 can be used for the research of cancer[1].
Related Catalog
References

[1]. Y Tamura, et al. Highly selective and orally active inhibitors of type IV collagenase (MMP-9 and MMP-2): N-sulfonylamino acid derivatives. J Med Chem. 1998 Feb 12;41(4):640-9.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 595.9±60.0 °C at 760 mmHg
Molecular Formula C21H19NO4S
Molecular Weight 381.445
Flash Point 314.2±32.9 °C
Exact Mass 381.103485
LogP 4.47
Appearance of Characters powder | light brown
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.627
Storage condition 2-8°C

 Safety Information

Hazard Codes B,Xi
Risk Phrases 36/37/38-42
Safety Phrases 23-26-36-24/25
WGK Germany 2

 Synonyms

D-Phenylalanine, N-([1,1'-biphenyl]-4-ylsulfonyl)-
N-(Biphenyl-4-ylsulfonyl)-D-phenylalanine
N-(4-Biphenylylsulfonyl)-D-phenylalanine
Top Suppliers:I want be here


Get all suppliers and price by the below link:

gelatinase a suppliers

gelatinase a price