L-(N,N,O-2H3)Alanine

Modify Date: 2024-01-21 12:34:52

L-(N,N,O-2H3)Alanine structure	Common Name	L-(N,N,O-2H3)Alanine
	CAS Number	19470-97-4	Molecular Weight	92.112
	Density	1.2±0.1 g/cm3	Boiling Point	212.9±23.0 °C at 760 mmHg
	Molecular Formula	C₃H₄D₃NO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	82.6±22.6 °C

Use of L-(N,N,O-2H3)Alanine

L-Alanine-d3-1 is the deuterium labeled L-Alanine[1]. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system[2].

Name	l-alanine-n,n,o-d3
Synonym	More Synonyms

Description	L-Alanine-d3-1 is the deuterium labeled L-Alanine[1]. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system[2].
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Nagashima T, et al. Selective Elimination of Human Induced Pluripotent Stem Cells Using Medium with High Concentration of L-Alanine. Sci Rep. 2018 Aug 20;8(1):12427.

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Nagashima T, et al. Selective Elimination of Human Induced Pluripotent Stem Cells Using Medium with High Concentration of L-Alanine. Sci Rep. 2018 Aug 20;8(1):12427.

Density	1.2±0.1 g/cm3
Boiling Point	212.9±23.0 °C at 760 mmHg
Molecular Formula	C₃H₄D₃NO₂
Molecular Weight	92.112
Flash Point	82.6±22.6 °C
Exact Mass	92.066505
PSA	63.32000
LogP	-0.68
Vapour Pressure	0.1±0.9 mmHg at 25°C
Index of Refraction	1.460

L-alanine

CAS#:56-41-7

L-(N,N,O-2H3)Alanine

CAS#:19470-97-4

Literature: Susi, Heino; Byler, D. Michael Journal of Molecular Structure, 1980 , vol. 63, p. 1 - 12

Precursor 1
CAS#:56-41-7 L-alanine
DownStream 0

N,N,O-d3-Alanine

L-alanine-N-d3

alanine-N-d3

L-Alanyl-4-methoxy-2-naphthylamid

L-Alanine-N,N,1-d

L-alanine-d3

N,N,O-trideuterio-L-alanine

ND3-L-alanine

L-Alanine 4-methoxy-|A-naphthylamide

L-alanine-4-methoxy-2-naphthylamide hydrochloride

L-(N,N,O-H)Alanine

L-(N,N,O-2H3)Alanine

Use of L-(N,N,O-2H3)Alanine

Names

L-(N,N,O-2H3)Alanine Biological Activity

Chemical & Physical Properties

Synthetic Route

Precursor & DownStream

Synonyms