Cyclopentanecarboxylic acid, 2-amino-4-methylene-, (1R,2S)- (9CI)
Cyclopentanecarboxylic acid, 2-amino-4-methylene-, (1R,2S)- (9CI) structure
|
Common Name | Cyclopentanecarboxylic acid, 2-amino-4-methylene-, (1R,2S)- (9CI) | ||
|---|---|---|---|---|
| CAS Number | 198022-65-0 | Molecular Weight | 141.17 | |
| Density | 1.16g/cm3 | Boiling Point | 277.4ºC at 760 mmHg | |
| Molecular Formula | C7H11NO2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 121.6ºC | |
Use of Cyclopentanecarboxylic acid, 2-amino-4-methylene-, (1R,2S)- (9CI)Icofungipen is an orally active antifungal agent. Icofungipen is the representative of beta amino acids, is toxic against Candida species. Icofungipen protects infected mice survival from C. albicans infection[1]. |
| Name | icofungipen |
|---|---|
| Synonym | More Synonyms |
| Description | Icofungipen is an orally active antifungal agent. Icofungipen is the representative of beta amino acids, is toxic against Candida species. Icofungipen protects infected mice survival from C. albicans infection[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Icofungipen 对念珠菌有抑制作用，MIC 值为 16-64 μg/mL（24-48 h 处理时间）[1]。 Icofungipen 对 90% 的念珠菌的 MIC90 值为 8-32 μg/mL[1]。 |
| In Vivo | Icofungipen（5-25 mg/kg；口服；每天两次，持续 7 天）在小鼠感染的致死模型中，剂量依赖性保护小鼠抵御白色念珠菌临床分离株的感染[1]。 |
| References |
| Density | 1.16g/cm3 |
|---|---|
| Boiling Point | 277.4ºC at 760 mmHg |
| Molecular Formula | C7H11NO2 |
| Molecular Weight | 141.17 |
| Flash Point | 121.6ºC |
| Exact Mass | 141.07900 |
| PSA | 63.32000 |
| LogP | 1.06480 |
| Vapour Pressure | 0.00123mmHg at 25°C |
| Index of Refraction | 1.528 |
|
~86%
Cyclopentanecar... CAS#:198022-65-0 |
| Literature: Mittendorf, Joachim; Benet-Buchholz, Jordi; Fey, Peter; Mohrs, Klaus-Helmut Synthesis, 2003 , # 1 p. 136 - 140 |
|
~%
Cyclopentanecar... CAS#:198022-65-0 |
| Literature: Mittendorf, Joachim; Benet-Buchholz, Jordi; Fey, Peter; Mohrs, Klaus-Helmut Synthesis, 2003 , # 1 p. 136 - 140 |
|
~%
Cyclopentanecar... CAS#:198022-65-0 |
| Literature: Mittendorf, Joachim; Benet-Buchholz, Jordi; Fey, Peter; Mohrs, Klaus-Helmut Synthesis, 2003 , # 1 p. 136 - 140 |
|
~%
Cyclopentanecar... CAS#:198022-65-0 |
| Literature: Mittendorf, Joachim; Benet-Buchholz, Jordi; Fey, Peter; Mohrs, Klaus-Helmut Synthesis, 2003 , # 1 p. 136 - 140 |
|
~%
Cyclopentanecar... CAS#:198022-65-0 |
| Literature: Mittendorf, Joachim; Benet-Buchholz, Jordi; Fey, Peter; Mohrs, Klaus-Helmut Synthesis, 2003 , # 1 p. 136 - 140 |
|
~%
Cyclopentanecar... CAS#:198022-65-0 |
| Literature: Mittendorf, Joachim; Benet-Buchholz, Jordi; Fey, Peter; Mohrs, Klaus-Helmut Synthesis, 2003 , # 1 p. 136 - 140 |
|
~%
Cyclopentanecar... CAS#:198022-65-0 |
| Literature: Mittendorf, Joachim; Benet-Buchholz, Jordi; Fey, Peter; Mohrs, Klaus-Helmut Synthesis, 2003 , # 1 p. 136 - 140 |
|
~%
Cyclopentanecar... CAS#:198022-65-0 |
| Literature: Mittendorf, Joachim; Benet-Buchholz, Jordi; Fey, Peter; Mohrs, Klaus-Helmut Synthesis, 2003 , # 1 p. 136 - 140 |
|
~%
Cyclopentanecar... CAS#:198022-65-0 |
| Literature: Mittendorf, Joachim; Benet-Buchholz, Jordi; Fey, Peter; Mohrs, Klaus-Helmut Synthesis, 2003 , # 1 p. 136 - 140 |
![(2E)-3-phenyl-2-propenyl (1R,2S)-4-methylene-2-{[(2E)-3-phenyl-2-propenyloxycarbonyl]amino}cyclopentanecarboxylate structure](https://image.chemsrc.com/caspic/067/198022-62-7.png)
![5-methylenetetrahydrocyclopenta[c]furan-1,3-dione structure](https://image.chemsrc.com/caspic/392/139228-09-4.png)
![(+)-(1S,2R)-4-methylene-2-[(2E)-3-phenyl-2-propenyloxycarbonyl]cyclopentanecarboxylic acid structure](https://image.chemsrc.com/caspic/143/198022-60-5.png)
| Cyclopentane carboxylicacid,2-amino-4-methylene-,(1R,2S)-(9CI) |