Gefitinib impurity 5 structure
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Common Name | Gefitinib impurity 5 | ||
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CAS Number | 199327-61-2 | Molecular Weight | 319.356 | |
Density | 1.3±0.1 g/cm3 | Boiling Point | 564.4±50.0 °C at 760 mmHg | |
Molecular Formula | C16H21N3O4 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 295.2±30.1 °C |
Use of Gefitinib impurity 5Gefitinib impurity 5 is the impurity of Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity[1][2]. |
Name | 7-methoxy-6-(3-morpholin-4-ylpropoxy)-1H-quinazolin-4-one |
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Synonym | More Synonyms |
Description | Gefitinib impurity 5 is the impurity of Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity[1][2]. |
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Related Catalog | |
References |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 564.4±50.0 °C at 760 mmHg |
Molecular Formula | C16H21N3O4 |
Molecular Weight | 319.356 |
Flash Point | 295.2±30.1 °C |
Exact Mass | 319.153198 |
PSA | 76.68000 |
LogP | 0.29 |
Vapour Pressure | 0.0±1.5 mmHg at 25°C |
Index of Refraction | 1.611 |
Storage condition | 2~8℃ |
Hazard Codes | Xi |
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HS Code | 2934999090 |
Precursor 8 | |
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DownStream 2 | |
HS Code | 2934999090 |
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Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
4(3H)-Quinazolinone, 7-methoxy-6-[3-(4-morpholinyl)propoxy]- |
7-Methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4(3H)-one |
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one |
7-Methoxy-6-[3-(4-morpholinyl)propoxy]-4(1H)-quinazolinone |
Gefitinib Impurity 17 |