ZINC194100678

Modify Date: 2024-01-03 10:51:19

ZINC194100678 structure	Common Name	ZINC194100678
	CAS Number	1995025-05-2	Molecular Weight	219.24
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₀H₁₃N₅O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ZINC194100678

ZINC194100678 is a potent PAK1 inhibitor with an IC50 value of 8.37 μM. ZINC194100678 can inhibit MDA-MB-231 cell proliferation. ZINC194100678 can be used for researching anticancer[1].

Name	ZINC194100678

Description	ZINC194100678 is a potent PAK1 inhibitor with an IC50 value of 8.37 μM. ZINC194100678 can inhibit MDA-MB-231 cell proliferation. ZINC194100678 can be used for researching anticancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cytoskeleton >> PAK Signaling Pathways >> Cell Cycle/DNA Damage >> PAK
Target	PAK1:8.37 μM (IC50)
In Vitro	ZINC194100678 (0-50 μM; 48 hours) exhibits potent antiproliferative activity with an IC50 value of 40.16 μM[1]. Cell Proliferation Assay Cell Line: MDA-MB-231[1] Concentration: 0-50 μM Incubation Time: 48 hours Result: Exhibited potent antiproliferative activity with an IC50 value of 40.16 μM.
References	[1]. Zhang J, et al. Design, synthesis and biological evaluation of 1H-pyrazolo [3,4-d]pyrimidine derivatives as PAK1 inhibitors that trigger apoptosis, ER stress and anti-migration effect in MDA-MB-231 cells. Eur J Med Chem. 2020;194:112220.

Molecular Formula	C₁₀H₁₃N₅O
Molecular Weight	219.24

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