UB 165 fumarate

Modify Date: 2024-01-09 09:54:28

UB 165 fumarate Structure
UB 165 fumarate structure
Common Name UB 165 fumarate
CAS Number 200432-86-6 Molecular Weight 350.79700
Density N/A Boiling Point 597.4ºC at 760mmHg
Molecular Formula C17H19ClN2O4 Melting Point N/A
MSDS N/A Flash Point 315.1ºC

 Use of UB 165 fumarate


UB-165 is a nAChR agonist, being a full agonist of the α3β2 isoform and a partial agonist of the α4β2* isoform, with a Ki value of 0.27 nM for [3H]-nicotine binding in rat brain[1].

 Names

Name UB 165 fumarate,2-(6-Chloro-3-pyridinyl)-9-azabicyclo[4.2.1]non-2-enefumarate
Synonym More Synonyms

 UB 165 fumarate Biological Activity

Description UB-165 is a nAChR agonist, being a full agonist of the α3β2 isoform and a partial agonist of the α4β2* isoform, with a Ki value of 0.27 nM for [3H]-nicotine binding in rat brain[1].
Related Catalog
In Vitro UB-165 刺激 [3H]-多巴胺从纹状体突触释放,EC50 值为 88 nM[1]。
References

[1]. Sharples CG, et al. UB-165: a novel nicotinic agonist with subtype selectivity implicates the alpha4beta2* subtype in the modulation of dopamine release from rat striatal synaptosomes. J Neurosci. 2000 Apr 15;20(8):2783-91.  

 Chemical & Physical Properties

Boiling Point 597.4ºC at 760mmHg
Molecular Formula C17H19ClN2O4
Molecular Weight 350.79700
Flash Point 315.1ºC
Exact Mass 350.10300
PSA 99.52000
LogP 3.07340

 Synonyms

Compound 401
UB 165 FUMARATE
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