IRAP-IN-1
Modify Date: 2024-09-08 07:51:31
IRAP-IN-1 structure
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Common Name | IRAP-IN-1 | ||
|---|---|---|---|---|
| CAS Number | 2007955-25-9 | Molecular Weight | 597.696 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C35H40N3O4P | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of IRAP-IN-1IRAP-IN-1 is a selective insulin-regulated aminopeptidase (IRAP) inhibitor with IC50 of 32 nM, >25-fold selectivity over ERAP1 and ERAP2.IRAP-IN-1 reduces IRAP-dependent but not ERAP1-dependent cross-presentation by dendritic cells with nanomolar efficacy. |
| Name | IRAP-IN-1 |
|---|
| Description | IRAP-IN-1 is a selective insulin-regulated aminopeptidase (IRAP) inhibitor with IC50 of 32 nM, >25-fold selectivity over ERAP1 and ERAP2.IRAP-IN-1 reduces IRAP-dependent but not ERAP1-dependent cross-presentation by dendritic cells with nanomolar efficacy. |
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| References | 1. Paraskevi Kokkala, et al. J Med Chem. 2016 Oct 13;59(19):9107-9123. |
| Molecular Formula | C35H40N3O4P |
|---|---|
| Molecular Weight | 597.696 |