Tenuifolin structure
|
Common Name | Tenuifolin | ||
---|---|---|---|---|
CAS Number | 20183-47-5 | Molecular Weight | 680.823 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | 853.6±65.0 °C at 760 mmHg | |
Molecular Formula | C36H56O12 | Melting Point | 201-204℃ | |
MSDS | N/A | Flash Point | 262.2±27.8 °C |
Use of TenuifolinTenuifolin is a triterpene isolated from Polygala tenuifolia Willd, has neuroprotective effects. Tenuifolin reduces Aβ secretion by inhibiting β-secretase. Tenuifolin improves learning and memory in aged mice by decreasing AChE activity and has the potential for Alzheimer’s disease (AD) treatment[1]. |
Name | (2β,3β)-3-(β-D-Glucopyranosyloxy)-2,27-dihydroxyolean-12-ene-23,2 8-dioic acid |
---|---|
Synonym | More Synonyms |
Description | Tenuifolin is a triterpene isolated from Polygala tenuifolia Willd, has neuroprotective effects. Tenuifolin reduces Aβ secretion by inhibiting β-secretase. Tenuifolin improves learning and memory in aged mice by decreasing AChE activity and has the potential for Alzheimer’s disease (AD) treatment[1]. |
---|---|
Related Catalog | |
Target |
IC50: β-secretase; ACHE[1] |
References |
Density | 1.4±0.1 g/cm3 |
---|---|
Boiling Point | 853.6±65.0 °C at 760 mmHg |
Melting Point | 201-204℃ |
Molecular Formula | C36H56O12 |
Molecular Weight | 680.823 |
Flash Point | 262.2±27.8 °C |
Exact Mass | 680.377197 |
PSA | 214.44000 |
LogP | 2.25 |
Vapour Pressure | 0.0±0.6 mmHg at 25°C |
Index of Refraction | 1.623 |
Safety Phrases | 24/25 |
---|---|
HS Code | 29389090 |
~% Tenuifolin CAS#:20183-47-5 |
Literature: Chemical and Pharmaceutical Bulletin, , vol. 30, # 3 p. 810 - 821 |
~% Tenuifolin CAS#:20183-47-5 |
Literature: Chemical and Pharmaceutical Bulletin, , vol. 30, # 3 p. 810 - 821 |
Precursor 2 | |
---|---|
DownStream 0 |
(2β,3β)-3-(β-D-Glucopyranosyloxy)-2,27-dihydroxyolean-12-ene-24,28-dioic acid |
Olean-12-ene-23,28-dioic acid, 3-(β-D-glucopyranosyloxy)-2,27-dihydroxy-, (2β,3β)- |
Tenuifolin |
Olean-12-ene-24,28-dioic acid, 3-(β-D-glucopyranosyloxy)-2,27-dihydroxy-, (2β,3β)- |
(2β,3β)-3-(β-D-Glucopyranosyloxy)-2,27-dihydroxyolean-12-ene-23,28-dioic acid |