(E)-3-(4-Methoxyphenyl)acrylic acid

Modify Date: 2024-01-09 14:02:30

(E)-3-(4-Methoxyphenyl)acrylic acid Structure
(E)-3-(4-Methoxyphenyl)acrylic acid structure
Common Name (E)-3-(4-Methoxyphenyl)acrylic acid
CAS Number 943-89-5 Molecular Weight 178.185
Density 1.2±0.1 g/cm3 Boiling Point 342.6±17.0 °C at 760 mmHg
Molecular Formula C10H10O3 Melting Point 173.5ºC
MSDS Chinese USA Flash Point 138.6±14.4 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of (E)-3-(4-Methoxyphenyl)acrylic acid


(E)-3-(4-Methoxyphenyl)acrylic acid (compound 3) is isolated from Arachis hypogaea, Scrophularia buergeriana Miquel, Aquilegia vulgaris, Anigozanthos preissii and so on. (E)-3-(4-Methoxyphenyl)acrylic acid shows significant hepatoprotective activity, anti-amnesic, cognition-enhancing activity, antihyperglycemic, and neuroprotective activities[1].

 Names

Name (E)-4-Methoxycinnamic Acid
Synonym More Synonyms

 (E)-3-(4-Methoxyphenyl)acrylic acid Biological Activity

Description (E)-3-(4-Methoxyphenyl)acrylic acid (compound 3) is isolated from Arachis hypogaea, Scrophularia buergeriana Miquel, Aquilegia vulgaris, Anigozanthos preissii and so on. (E)-3-(4-Methoxyphenyl)acrylic acid shows significant hepatoprotective activity, anti-amnesic, cognition-enhancing activity, antihyperglycemic, and neuroprotective activities[1].
Related Catalog
References

[1]. Sirichan Tachai, et al. Uncommon secondary metabolites from Etlingera pavieana rhizomes. Nat Prod Res. 2016 Oct;30(19):2215-9.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 342.6±17.0 °C at 760 mmHg
Melting Point 173.5ºC
Molecular Formula C10H10O3
Molecular Weight 178.185
Flash Point 138.6±14.4 °C
Exact Mass 178.062988
PSA 46.53000
LogP 2.36
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.591

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS UD3391300
HS Code 2916399090

 Synthetic Route

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles21

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The number of multidrug resistant (MDR) microorganisms is increasing and the antimicrobial resistance expressed by these pathogens is generating a rising global health crisis. In fact, there are only ...

A practical procedure for the large-scale preparation of methyl (2R,3S)-3-(4-methoxyphenyl)glycidate, a key intermediate for diltiazem.

J. Org. Chem. 67(13) , 4599-601, (2002)

A practical synthesis of methyl (2R,3S)-3-(4-methoxyphenyl)glycidate (-)-2, a key intermediate for diltiazem (1), was developed. Treatment of methyl (E)-4-methoxycinnamate 3 with chiral dioxirane, gen...

Enzymatic synthesis of cinnamic acid derivatives.

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Using Novozym 435 as catalyst, the syntheses of ethyl ferulate (EF) from ferulic acid (4-hydroxy 3-methoxy cinnamic acid) and ethanol, and octyl methoxycinnamate (OMC) from p-methoxycinnamic acid and ...

 Synonyms

3-(4-Methoxy-phenyl)-acrylic acid
trans-4-Methoxycinnamic acid
4-MeOC6H4CH=CHCOOH
4-methoxycinnamate
RARECHEM BK HC T257
2-Propenoic acid, 3-(4-methoxyphenyl)-, (2E)-
2-Propenoic acid, 3- (4-methoxyphenyl)-
(E)-3-(4-methoxyphenyl)acrylic acid
4-Methoxy-(2E)-cinnamic acid
4-Methoxyciamic acid
p-coumaric acid methyl ether
(2E)-3-(4-methoxyphenyl)prop-2-enoic acid
UNII-6G4ML8401A
(E)-p-methoxycinnamic acid
4-Methoxycinnamic acid
(2E)-3-(4-Methoxyphenyl)acrylic acid
4-methoxy-(E)-cinnamic acid
EINECS 213-405-4
(E)-3-(4-Methoxyphenyl)acrylate
para-methoxycinnamic acid
PMCA
MFCD00004398
(2E)-3-(4-Methoxyphenyl)-2-propenoic acid
para-methoxycinnamate
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