1,2, 4-Triazine-3,5 (2H,4H)-dione, 2-(2-deoxy-.beta.-D-erythro-pentofuranosyl)-

Modify Date: 2024-01-23 17:42:20

1,2, 4-Triazine-3,5 (2H,4H)-dione, 2-(2-deoxy-.beta.-D-erythro-pentofuranosyl)- Structure
1,2, 4-Triazine-3,5 (2H,4H)-dione, 2-(2-deoxy-.beta.-D-erythro-pentofuranosyl)- structure
Common Name 1,2, 4-Triazine-3,5 (2H,4H)-dione, 2-(2-deoxy-.beta.-D-erythro-pentofuranosyl)-
CAS Number 20500-29-2 Molecular Weight 229.19
Density 1.9g/cm3 Boiling Point N/A
Molecular Formula C8H11N3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1,2, 4-Triazine-3,5 (2H,4H)-dione, 2-(2-deoxy-.beta.-D-erythro-pentofuranosyl)-


6-Aza-2'-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazine-3,5-dione
Synonym More Synonyms

  Biological Activity

Description 6-Aza-2'-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.9g/cm3
Molecular Formula C8H11N3O5
Molecular Weight 229.19
Exact Mass 229.07000
PSA 117.44000
Index of Refraction 1.753

 Synonyms

6'-aza-2'deoxyuridine
6-Azauridine deoxyribonucleoside
2'-Deoxy-6-azauridine