m-PEG3-Sulfone-PEG4-propargyl

Modify Date: 2024-01-03 10:15:20

m-PEG3-Sulfone-PEG4-propargyl structure	Common Name	m-PEG3-Sulfone-PEG4-propargyl
	CAS Number	2055041-02-4	Molecular Weight	426.52
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₃₄O₉S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of m-PEG3-Sulfone-PEG4-propargyl

m-PEG3-Sulfone-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	m-PEG3-Sulfone-PEG4-propargyl
Synonym	More Synonyms

Description	m-PEG3-Sulfone-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₈H₃₄O₉S
Molecular Weight	426.52

MFCD29918252