PF-06678419

Modify Date: 2023-01-16 21:04:10

PF-06678419 Structure
PF-06678419 structure
Common Name PF-06678419
CAS Number 2055468-48-7 Molecular Weight 364.135
Density N/A Boiling Point N/A
Molecular Formula C12H13IO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PF-06678419


PF-06678419 (PF06678419) is a potent, selective inhibitor of the Na+/citrate transporter NaCT (SLC13A5) that shows inhibition of citrate uptake in the HEKNaCT cells with IC50 of 0.44 uM; displays relatively selectivity over NaDC1 and NaDC3 (7-10-fold).

 Names

Name PF-06678419

 PF-06678419 Biological Activity

Description PF-06678419 (PF06678419) is a potent, selective inhibitor of the Na+/citrate transporter NaCT (SLC13A5) that shows inhibition of citrate uptake in the HEKNaCT cells with IC50 of 0.44 uM; displays relatively selectivity over NaDC1 and NaDC3 (7-10-fold).
References References 1. Pajor AM, et al. Mol Pharmacol. 2016 Dec;90(6):755-765. 2. Huard K, et al. Sci Rep. 2015 Dec 1;5:17391. View Related Products by Target Sodium-coupled Citrate Transporter (NaCT,SLC13A5)

 Chemical & Physical Properties

Molecular Formula C12H13IO5
Molecular Weight 364.135
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