Capsiate

Modify Date: 2024-01-10 09:38:27

Capsiate Structure
Capsiate structure
 Common Name Capsiate
CAS Number 205687-01-0 Molecular Weight 306.39700
Density N/A Boiling Point 421.3±40.0 °C(Predicted)
Molecular Formula C18H26O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Capsiate


Capsiate, as a capsaicin analogue extracted from a non-pungent cultivar of CH-19 sweet red pepper, is an orally active agonist of TRPV1[1].

 Names

Name (4-hydroxy-3-methoxyphenyl)methyl (E)-8-methylnon-6-enoate
Synonym More Synonyms

 Capsiate Biological Activity

Description Capsiate, as a capsaicin analogue extracted from a non-pungent cultivar of CH-19 sweet red pepper, is an orally active agonist of TRPV1[1].
Related Catalog
Target

TRPV1

In Vitro Capsiate evokes current responses in HEK293 cells expressing TRPV1[1].
In Vivo Capsiate does not exhibit irritancy-related effects on the oral cavity or eye[1]. Capsiate (0.03~0.54 mM; s.c.) induces nociceptive responses in mice[1]. Animal Model: Male ddY-strain mice (20–24 g) [1] Dosage: 0.5 or 5 mM Administration: P.o. Result: Did not cause pungency-related behaviors.
References

[1]. Iida T, et al. TRPV1 activation and induction of nociceptive response by a non-pungent capsaicin-like compound, capsiate. Neuropharmacology. 2003;44(7):958-967.

 Chemical & Physical Properties

Boiling Point 421.3±40.0 °C(Predicted)
Molecular Formula C18H26O4
Molecular Weight 306.39700
Exact Mass 306.18300
PSA 55.76000
LogP 4.21660

 Synthetic Route

8-METHYLNON-6-ENOIC ACID structure

8-METHYLNON-6-E...

CAS#:59320-77-3

Vanillyl alcohol structure

Vanillyl alcohol

CAS#:498-00-0

~88%

Capsiate Structure

Capsiate

CAS#:205687-01-0

Literature: AJINOMOTO CO., INC. Patent: WO2006/88239 A1, 2006 ; Location in patent: Page/Page column 40-41 ;
4-t-butyldimethylsilyloxy-3-methoxybenzyl (E)-8-methylnon-6-enoate structure

4-t-butyldimeth...

CAS#:1073340-78-9

~79%

Capsiate Structure

Capsiate

CAS#:205687-01-0

Literature: Barbero, Gerardo F.; Molinillo, Jose M. G.; Varela, Rosa M.; Palma, Miguel; MacIas, Francisco A.; Barroso, Carmelo G. Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 6 p. 3342 - 3349
8-METHYLNON-6-ENOIC ACID structure

8-METHYLNON-6-E...

CAS#:59320-77-3

~%

Capsiate Structure

Capsiate

CAS#:205687-01-0

Literature: Barbero, Gerardo F.; Molinillo, Jose M. G.; Varela, Rosa M.; Palma, Miguel; MacIas, Francisco A.; Barroso, Carmelo G. Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 6 p. 3342 - 3349
4-[tert-butyl(dimethyl)silyl]oxy-3-methoxybenzaldehyde structure

4-[tert-butyl(d...

CAS#:69404-94-0

~%

Capsiate Structure

Capsiate

CAS#:205687-01-0

Literature: Barbero, Gerardo F.; Molinillo, Jose M. G.; Varela, Rosa M.; Palma, Miguel; MacIas, Francisco A.; Barroso, Carmelo G. Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 6 p. 3342 - 3349
Vanillin structure

Vanillin

CAS#:121-33-5

~%

Capsiate Structure

Capsiate

CAS#:205687-01-0

Literature: Barbero, Gerardo F.; Molinillo, Jose M. G.; Varela, Rosa M.; Palma, Miguel; MacIas, Francisco A.; Barroso, Carmelo G. Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 6 p. 3342 - 3349
CIS 8-METHYLNON-6-ENOIC ACID structure

CIS 8-METHYLNON...

CAS#:31467-60-4

~%

Capsiate Structure

Capsiate

CAS#:205687-01-0

Literature: Barbero, Gerardo F.; Molinillo, Jose M. G.; Varela, Rosa M.; Palma, Miguel; MacIas, Francisco A.; Barroso, Carmelo G. Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 6 p. 3342 - 3349
TRANS-8-METHYL-6-NONENOYL CHLORIDE structure

TRANS-8-METHYL-...

CAS#:95636-02-5

4-[(tert-butyldimethylsilyl)oxy]-3-methoxybenzyl alcohol structure

4-[(tert-butyld...

CAS#:113931-96-7

~%

Capsiate Structure

Capsiate

CAS#:205687-01-0

Literature: Barbero, Gerardo F.; Molinillo, Jose M. G.; Varela, Rosa M.; Palma, Miguel; MacIas, Francisco A.; Barroso, Carmelo G. Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 6 p. 3342 - 3349

 Synonyms

Capsiate Natura
UNII-PX8I7HG5I3
capsiate
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Chemsrc provides Capsiate(CAS#:205687-01-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Capsiate are included as well.>> amp version: Capsiate

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