dTAG-7 structure
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Common Name | dTAG-7 | ||
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CAS Number | 2064175-32-0 | Molecular Weight | 1210.32 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C63H79N5O19 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of dTAG-7FKBP12 PROTAC dTAG-7 (dTAG-7) is a heterobifunctional degrader. FKBP12 PROTAC dTAG-7 (dTAG-7) is a degrader of FKBP12F36V with expression of FKBP12F36V in-frame with a protein of interest. FKBP12 PROTAC dTAG-7 (dTAG-7) also is a selective degrader of BET bromodomain transcriptional co-activator BRD4 by bridging BET bromodomains to an E3 ubiquitin ligase CRBN[1]. |
Name | FKBP12 PROTAC dTAG-7 |
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Description | FKBP12 PROTAC dTAG-7 (dTAG-7) is a heterobifunctional degrader. FKBP12 PROTAC dTAG-7 (dTAG-7) is a degrader of FKBP12F36V with expression of FKBP12F36V in-frame with a protein of interest. FKBP12 PROTAC dTAG-7 (dTAG-7) also is a selective degrader of BET bromodomain transcriptional co-activator BRD4 by bridging BET bromodomains to an E3 ubiquitin ligase CRBN[1]. |
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Related Catalog | |
Target |
FKBP12(F36V) BRD4 Cereblon |
References |
Molecular Formula | C63H79N5O19 |
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Molecular Weight | 1210.32 |