2′-O-2-Propyn-1-ylguanosine

Modify Date: 2024-01-11 11:16:49

2′-O-2-Propyn-1-ylguanosine structure	Common Name	2′-O-2-Propyn-1-ylguanosine
	CAS Number	206552-86-5	Molecular Weight	321.29
	Density	1.8±0.1 g/cm3	Boiling Point	737.5±70.0 °C at 760 mmHg
	Molecular Formula	C₁₃H₁₅N₅O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	399.8±35.7 °C

Use of 2′-O-2-Propyn-1-ylguanosine

2′-O-2-Propyn-1-ylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

Name	2'-O-2-Propyn-1-ylguanosine
Synonym	More Synonyms

Description	2′-O-2-Propyn-1-ylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.

Density	1.8±0.1 g/cm3
Boiling Point	737.5±70.0 °C at 760 mmHg
Molecular Formula	C₁₃H₁₅N₅O₅
Molecular Weight	321.29
Flash Point	399.8±35.7 °C
Exact Mass	321.107330
LogP	0.31
Vapour Pressure	0.0±2.5 mmHg at 25°C
Index of Refraction	1.761

2'-O-2-Propyn-1-ylguanosine

Guanosine, 2'-O-2-propyn-1-yl-

2′-O-2-Propyn-1-ylguanosine

Use of 2′-O-2-Propyn-1-ylguanosine

Names

2′-O-2-Propyn-1-ylguanosine Biological Activity

Chemical & Physical Properties

Synonyms