PROTAC FKBP Degrader-3
Modify Date: 2024-01-10 08:42:40
PROTAC FKBP Degrader-3 structure
|
Common Name | PROTAC FKBP Degrader-3 | ||
|---|---|---|---|---|
| CAS Number | 2079056-43-0 | Molecular Weight | 1295.54 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C68H90N6O17S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PROTAC FKBP Degrader-3PROTAC FKBP Degrader-3 is a PROTAC that comprises a FKBP ligand binding group, a linker and an VHL binding group. PROTAC FKBP Degrader-3 is a potent FKBP degrader[1]. |
| Name | PROTAC FKBP Degrader-3 |
|---|
| Description | PROTAC FKBP Degrader-3 is a PROTAC that comprises a FKBP ligand binding group, a linker and an VHL binding group. PROTAC FKBP Degrader-3 is a potent FKBP degrader[1]. |
|---|---|
| Related Catalog | |
| Target |
VHL FKBP |
| In Vitro | PROTAC treatment time courses demonstrated a notable increase in polyubiquitination of EGFP-FKBP in response to treatment with 250 nM of PROTAC FKBP Degrader-3 (compound 10) for VHL within the first hour. Upon recruiting endogenous VHL via PROTAC FKBP Degrader-3 (compound 10), only one EGFP background lysine (Lys158) is found to be ubiquitylated[1]. |
| References |
| Molecular Formula | C68H90N6O17S |
|---|---|
| Molecular Weight | 1295.54 |
| Storage condition | -20°C |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: PROTAC FKBP Degrader-3
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
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Price: ￥6800/1 mg
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