PROTAC ER Degrader-3

Modify Date: 2024-01-07 17:27:55

PROTAC ER Degrader-3 Structure
PROTAC ER Degrader-3 structure
Common Name PROTAC ER Degrader-3
CAS Number 2158322-29-1 Molecular Weight 1220.41
Density N/A Boiling Point N/A
Molecular Formula C71H77N7O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PROTAC ER Degrader-3


PROTAC ER Degrader-3 is an intermediate for synthesis of PAC. PAC comprises an antibody conjugated via a linker to a PROTAC. PAC extracts from patent WO2017201449A1, compound LP2. PAC is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab).

 Names

Name PROTAC ER Degrader-3

 PROTAC ER Degrader-3 Biological Activity

Description PROTAC ER Degrader-3 is an intermediate for synthesis of PAC. PAC comprises an antibody conjugated via a linker to a PROTAC. PAC extracts from patent WO2017201449A1, compound LP2. PAC is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab).
Related Catalog
References

[1]. Thomas Pillow, et al. Protac antibody conjugates and methods of use. WO2017201449A1.

 Chemical & Physical Properties

Molecular Formula C71H77N7O12
Molecular Weight 1220.41
Storage condition 2-8℃