CDK2 inhibitor 73

Modify Date: 2024-01-07 21:45:14

CDK2 inhibitor 73 Structure
CDK2 inhibitor 73 structure
Common Name CDK2 inhibitor 73
CAS Number 2079895-42-2 Molecular Weight 442.49
Density N/A Boiling Point N/A
Molecular Formula C23H18N6O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CDK2 inhibitor 73


CDK2-IN-4 is a potent and selective CDK2 inhibitor with an IC50 of 44 nM for CDK2/cyclin A, shows 2,000-fold selectivity over CDK1/cyclin B (IC50=86 uM)[1].

 Names

Name CDK2-IN-4

 CDK2 inhibitor 73 Biological Activity

Description CDK2-IN-4 is a potent and selective CDK2 inhibitor with an IC50 of 44 nM for CDK2/cyclin A, shows 2,000-fold selectivity over CDK1/cyclin B (IC50=86 uM)[1].
Related Catalog
Target

cdk2/cyclin A:44 nM (IC50)

Cdk1/cyclin B:86 μM (IC50)

References

[1]. Coxon CR, et al. Cyclin-Dependent Kinase (CDK) Inhibitors: Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines. J Med Chem. 2017 Mar 9;60(5):1746-1767.

 Chemical & Physical Properties

Molecular Formula C23H18N6O2S
Molecular Weight 442.49
Storage condition 2-8℃
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