m-PEG7-azide

Modify Date: 2024-01-02 18:19:10

m-PEG7-azide Structure
m-PEG7-azide structure
Common Name m-PEG7-azide
CAS Number 208987-04-6 Molecular Weight 365.42300
Density N/A Boiling Point N/A
Molecular Formula C15H31N3O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG7-azide


m-PEG7-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

 Names

Name 1-azido-2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethane
Synonym More Synonyms

 m-PEG7-azide Biological Activity

Description m-PEG7-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.

 Chemical & Physical Properties

Molecular Formula C15H31N3O7
Molecular Weight 365.42300
Exact Mass 365.21600
PSA 114.36000
LogP 0.49546

 Synthetic Route

~75%

m-PEG7-azide Structure

m-PEG7-azide

CAS#:208987-04-6

Literature: Kurniasih, Indah N.; Liang, Hua; Moeschwitzer, Vicki D.; Quadir, Mohiuddin A.; Radowski, Michal; Rabe, Juergen P.; Haag, Rainer New Journal of Chemistry, 2012 , vol. 36, # 2 p. 371 - 379

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m-PEG7-azide Structure

m-PEG7-azide

CAS#:208987-04-6

Literature: Pan, Xusong; Chen, Chao; Peng, Jiang; Yang, Yongan; Wang, Yinghan; Feng, Wen; Deng, Pengchi; Yuan, Lihua Chemical Communications, 2012 , vol. 48, # 76 p. 9510 - 9512

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m-PEG7-azide Structure

m-PEG7-azide

CAS#:208987-04-6

Literature: Pan, Xusong; Chen, Chao; Peng, Jiang; Yang, Yongan; Wang, Yinghan; Feng, Wen; Deng, Pengchi; Yuan, Lihua Chemical Communications, 2012 , vol. 48, # 76 p. 9510 - 9512

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

azidoheptaethylene glycol methyl ether
2,5,8,11,14,17,20-Heptaoxadocosane,22-azido
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