208987-04-6
208987-04-6 structure
- Name: m-PEG7-azide
- Chemical Name: 1-azido-2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethane
- CAS Number: 208987-04-6
- Molecular Formula: C15H31N3O7
- Molecular Weight: 365.42300
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-11 08:48:31
- Modify Date: 2024-01-02 18:19:10
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m-PEG7-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
| Name | 1-azido-2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethane |
|---|---|
| Synonyms |
azidoheptaethylene glycol methyl ether
2,5,8,11,14,17,20-Heptaoxadocosane,22-azido |
| Description | m-PEG7-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
|---|---|
| Related Catalog | |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| References |
| Molecular Formula | C15H31N3O7 |
|---|---|
| Molecular Weight | 365.42300 |
| Exact Mass | 365.21600 |
| PSA | 114.36000 |
| LogP | 0.49546 |
|
~75%
208987-04-6 |
| Literature: Kurniasih, Indah N.; Liang, Hua; Moeschwitzer, Vicki D.; Quadir, Mohiuddin A.; Radowski, Michal; Rabe, Juergen P.; Haag, Rainer New Journal of Chemistry, 2012 , vol. 36, # 2 p. 371 - 379 |
|
~%
208987-04-6 |
| Literature: Pan, Xusong; Chen, Chao; Peng, Jiang; Yang, Yongan; Wang, Yinghan; Feng, Wen; Deng, Pengchi; Yuan, Lihua Chemical Communications, 2012 , vol. 48, # 76 p. 9510 - 9512 |
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~%
208987-04-6 |
| Literature: Pan, Xusong; Chen, Chao; Peng, Jiang; Yang, Yongan; Wang, Yinghan; Feng, Wen; Deng, Pengchi; Yuan, Lihua Chemical Communications, 2012 , vol. 48, # 76 p. 9510 - 9512 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |