N-Azido-PEG4-N-Boc-N-PEG3-Boc

Modify Date: 2024-01-09 09:58:40

N-Azido-PEG4-N-Boc-N-PEG3-Boc Structure
N-Azido-PEG4-N-Boc-N-PEG3-Boc structure
Common Name N-Azido-PEG4-N-Boc-N-PEG3-Boc
CAS Number 2093152-85-1 Molecular Weight 622.75
Density N/A Boiling Point N/A
Molecular Formula C28H54N4O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-Azido-PEG4-N-Boc-N-PEG3-Boc


N-Azido-PEG4-N-Boc-N-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-Azido-PEG4-N-Boc-N-PEG3-Boc

 N-Azido-PEG4-N-Boc-N-PEG3-Boc Biological Activity

Description N-Azido-PEG4-N-Boc-N-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C28H54N4O11
Molecular Weight 622.75

 Safety Information

Hazard Codes Xi