BAY-850

Modify Date: 2024-01-03 12:36:59

BAY-850 structure	Common Name	BAY-850
	CAS Number	2099142-76-2	Molecular Weight	654.24
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₈H₄₄ClN₅O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BAY-850

BAY-850 is a potent and isoform selective ATPase family AAA domain-containing protein 2 (ATAD2) inhibitor, with an IC50 of 166 nM.

Name	BAY-850

Description	BAY-850 is a potent and isoform selective ATPase family AAA domain-containing protein 2 (ATAD2) inhibitor, with an IC50 of 166 nM.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
Target	ATAD2[1].
In Vitro	BAY-850 competes with the binding of a mono-acetylated Histone H4 N-terminal peptide to ATAD2 BD with an IC50 of 166 nM measured in TR-FRET assay. BAY-850 displaces the tetra-acetylated peptide with an IC50 of 157 nM and a KD of 115 nM respectively. The unprecedented isoform selectivity of BAY-850 suggests a different mode of action to those exhibited by canonical BD inhibitors[1].
References	[1]. Fernández-Montalván AE, et al. Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action. ACS Chem Biol. 2017 Nov 17;12(11):2730-2736.

Molecular Formula	C₃₈H₄₄ClN₅O₃
Molecular Weight	654.24

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: BAY-850
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: BAY-850
Price: $950.0/100mg $1700.0/250mg $3400.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: BAY-850
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

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