N-(Amino-PEG4)-N-Biotin-PEG4-acid

Modify Date: 2024-01-13 23:47:45

N-(Amino-PEG4)-N-Biotin-PEG4-acid structure	Common Name	N-(Amino-PEG4)-N-Biotin-PEG4-acid
	CAS Number	2100306-84-9	Molecular Weight	710.88
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₁H₅₈N₄O₁₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of N-(Amino-PEG4)-N-Biotin-PEG4-acid

N-(Amino-PEG4)-N-Biotin-PEG4-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-(Amino-PEG4)-N-Biotin-PEG4-acid

Description	N-(Amino-PEG4)-N-Biotin-PEG4-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.

Molecular Formula	C₃₁H₅₈N₄O₁₂S
Molecular Weight	710.88

Hazard Codes	Xi