1-[(2S)-2-Aminopropyl]-1H-indazol-6-ol

Modify Date: 2024-01-28 18:37:28

1-[(2S)-2-Aminopropyl]-1H-indazol-6-ol structure	Common Name	1-[(2S)-2-Aminopropyl]-1H-indazol-6-ol
	CAS Number	210580-75-9	Molecular Weight	191.23
	Density	1.3±0.1 g/cm3	Boiling Point	372.8±22.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₁₃N₃O	Melting Point	N/A
	MSDS	N/A	Flash Point	179.2±22.3 °C

Use of 1-[(2S)-2-Aminopropyl]-1H-indazol-6-ol

AL-34662 is a selective 5-HT2A receptoragonist (IC50: 0.77 nM and 1.5 nM for rat and human 5-HT2 receptor). AL-34662 is also a weak α-1D adrenergic agonist activity (EC50:0.4 μM). AL-34662 is an ocular hypotensive agent[1][2].

Name	1-[(2S)-2-aminopropyl]-2H-indazol-6-one
Synonym	More Synonyms

Description	AL-34662 is a selective 5-HT2A receptoragonist (IC50: 0.77 nM and 1.5 nM for rat and human 5-HT2 receptor). AL-34662 is also a weak α-1D adrenergic agonist activity (EC50:0.4 μM). AL-34662 is an ocular hypotensive agent[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
Target	0.77 nM and 1.5 nM for rat and human 5-HT2 receptor[1]
References	[1]. Sharif NA, et al. AL-34662: a potent, selective, and efficacious ocular hypotensive serotonin-2 receptor agonist. J Ocul Pharmacol Ther. 2007 Feb;23(1):1-13. [2]. Asano T, et al. Ameliorative effect of chlorpromazine hydrochloride on visceral hypersensitivity in rats: possible involvement of 5-HT2A receptor. Br J Pharmacol. 2017 Oct;174(19):3370-3381.

Density	1.3±0.1 g/cm3
Boiling Point	372.8±22.0 °C at 760 mmHg
Molecular Formula	C₁₀H₁₃N₃O
Molecular Weight	191.23
Flash Point	179.2±22.3 °C
Exact Mass	191.105865
PSA	63.81000
LogP	0.81
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.652

1-[(2S)-2-Aminopropyl]-1H-indazol-6-ol

1-((S)-2-Amino-propyl)-1H-indazol-6; -ol

1-((S)-2-aminopropyl)-1H-indazol-6-ol

1H-Indazol-6-ol, 1-[(2S)-2-aminopropyl]-

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: AL 34662
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Al-34662
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1-((S)-2-AMINO-PROPYL)-1H-INDAZOL-6-OL
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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1-[(2S)-2-Aminopropyl]-1H-indazol-6-ol

Use of 1-[(2S)-2-Aminopropyl]-1H-indazol-6-ol

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