N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl)

Modify Date: 2024-01-09 13:20:08

N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl) Structure
N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl) structure
Common Name N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl)
CAS Number 2112737-60-5 Molecular Weight 604.73
Density N/A Boiling Point N/A
Molecular Formula C29H52N2O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl)


N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl)
Synonym More Synonyms

  Biological Activity

Description N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C29H52N2O11
Molecular Weight 604.73

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD30730360
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