BMS-1166 hydrochloride
Modify Date: 2024-01-03 20:09:26
BMS-1166 hydrochloride structure
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Common Name | BMS-1166 hydrochloride | ||
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| CAS Number | 2113650-05-6 | Molecular Weight | 677.57 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C36H34Cl2N2O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BMS-1166 hydrochlorideBMS-1166 hydrochloride is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation. |
| Name | BMS-1166 hydrochloride |
|---|
| Description | BMS-1166 hydrochloride is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation. |
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| Related Catalog | |
| Target |
IC50: 1.4 nM (PD-1/PD-L1 interaction)[1]. |
| In Vitro | BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM in a homogenous time-resolved fluorescence binding assay[1]. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation. BMS-1166 dose dependently abolishes the inhibition of ECs stimulation by sPD-L1[2]. |
| References |
| Molecular Formula | C36H34Cl2N2O7 |
|---|---|
| Molecular Weight | 677.57 |