Name | BMS-1166 hydrochloride |
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Description | BMS-1166 hydrochloride is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation. |
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Related Catalog | |
Target |
IC50: 1.4 nM (PD-1/PD-L1 interaction)[1]. |
In Vitro | BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM in a homogenous time-resolved fluorescence binding assay[1]. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation. BMS-1166 dose dependently abolishes the inhibition of ECs stimulation by sPD-L1[2]. |
References |
Molecular Formula | C36H34Cl2N2O7 |
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Molecular Weight | 677.57 |