Pa 155A
Modify Date: 2024-01-05 10:18:42
Pa 155A structure
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Common Name | Pa 155A | ||
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| CAS Number | 21200-24-8 | Molecular Weight | 257.288 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 420.8±37.0 °C at 760 mmHg | |
| Molecular Formula | C14H15N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 208.3±26.5 °C | |
Use of Pa 155AIndolmycin (TAK-083), an antibiotic, is a competitive inhibitor of prokaryotic tryptophanyl-tRNA ligase (TrpS). Indolmycin (TAK-083) possesses both anti-viral and anti-bacterial activity[1][2][3]. |
| Name | indolmycin |
|---|---|
| Synonym | More Synonyms |
| Description | Indolmycin (TAK-083), an antibiotic, is a competitive inhibitor of prokaryotic tryptophanyl-tRNA ligase (TrpS). Indolmycin (TAK-083) possesses both anti-viral and anti-bacterial activity[1][2][3]. |
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| Related Catalog | |
| In Vitro | Indolmycin was bacteriostatic and demonstrated good activity against MSSA (methicillinsusceptible Staphylococcus aureus), MRSA (methicillin-resistant S. aureus) and VISA (vancomycinintermediate S. aureus), including strains resistant to mupirocin or fusidic acid. Indolmycin MICs for 20 strains ranged from 8 to 32 mg/L, whereas asingle strain exhibited high-level resistance (MIC 128 mg/L)[2]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 420.8±37.0 °C at 760 mmHg |
| Molecular Formula | C14H15N3O2 |
| Molecular Weight | 257.288 |
| Flash Point | 208.3±26.5 °C |
| Exact Mass | 257.116425 |
| PSA | 69.97000 |
| LogP | 1.53 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.670 |
| HS Code | 2934999090 |
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| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| [S-(R*,S*)]-5-[1-(1H-Indol-3-yl)ethyl]-2-(methylamino)-4(5H)-oxazolone |
| (1R,5S)-(-)-5-(1-Indol-3-ylethyl)-2-(methylamino)-2-oxazolin-4-one |
| (5S)-5-[(1R)-1-(1H-Indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4(5H)-one |
| Indolemycin |
| 4(5H)-Oxazolone, 5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-, (5S)- |
| 2-Methylamino-5a-(b-indolyl)ethyl-2-oxazolin-4-one |
| Pa 155A |
| indolmycin |
| 2-Oxazolin-4-one,5-(1-indol-3-ylethyl)-2-(methylamino)-,(1R,5S)-(-) |
| 4(5H)-Oxazolone,5-(1-(1H-indol-3-yl)ethyl)-2-(methylamino)-,(S-(R*,S*)) |
| PA 155 A |
| 5-(1-Indol-3-ylethyl)-2-(methylamino)-2-oxazolin-4-one |
| Indomycin |
| (5S)-5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4-one |