Lenalidomide-C5-amido-Boc

Modify Date: 2024-01-09 15:21:53

Lenalidomide-C5-amido-Boc Structure
Lenalidomide-C5-amido-Boc structure
Common Name Lenalidomide-C5-amido-Boc
CAS Number 2138441-25-3 Molecular Weight 429.51
Density N/A Boiling Point N/A
Molecular Formula C23H31N3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Lenalidomide-C5-amido-Boc


Lenalidomide-C5-amido-Boc is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-amido-Boc can be connected to the ligand for protein by a linker to form PROTAC[1].

 Names

Name Lenalidomide-C5-amido-Boc

 Lenalidomide-C5-amido-Boc Biological Activity

Description Lenalidomide-C5-amido-Boc is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-amido-Boc can be connected to the ligand for protein by a linker to form PROTAC[1].
Related Catalog
Target

Cereblon

References

[1]. Wang, Shaomeng, et al. Preparation of phthalimide-based compounds as monofunctional intermediates for ligand-dependent target protein degradation. World Intellectual Property Organization, WO2017176958 A1 2017-10-12.

[2]. Robbins, Daniel, et al. WBifunctional compounds for degrading BTK via ubiquitin proteasome pathway. World Intellectual Property Organization, WO2021091575 A1 2021-05-14.

 Chemical & Physical Properties

Molecular Formula C23H31N3O5
Molecular Weight 429.51