2'-O-Methylguanosine

Modify Date: 2024-01-03 20:04:49

2'-O-Methylguanosine structure	Common Name	2'-O-Methylguanosine
	CAS Number	2140-71-8	Molecular Weight	297.267
	Density	2.0±0.1 g/cm3	Boiling Point	711.7ºC at 760 mmHg
	Molecular Formula	C₁₁H₁₅N₅O₅	Melting Point	218-220ºC
	MSDS	N/A	Flash Point	384.2ºC

Use of 2'-O-Methylguanosine

2'-O-Methylguanosine is a modified nucleoside produced in tRNAs by the action of tRNA guanosine-2’-O-methyltransferase. 2'-O-Methylguanosine results in apoptotic changes of cells[1][2].

Name	2'-O-methylguanosine
Synonym	More Synonyms

Description	2'-O-Methylguanosine is a modified nucleoside produced in tRNAs by the action of tRNA guanosine-2’-O-methyltransferase. 2'-O-Methylguanosine results in apoptotic changes of cells[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Metabolic Disease
References	[1]. B C Persson, et al. The spoU gene of Escherichia coli, the fourth gene of the spoT operon, is essential for tRNA (Gm18) 2'-O-methyltransferase activity. Nucleic Acids Res. 1997 Oct 15;25(20):4093-7. [2]. T Mori, et al. Isolation and identification of apoptosis inducing nucleosides from CD57(+)HLA-DRbright natural suppressor cell line. Biochem Biophys Res Commun. 1998 Oct 20;251(2):416-22.

Description

2'-O-Methylguanosine is a modified nucleoside produced in tRNAs by the action of tRNA guanosine-2’-O-methyltransferase. 2'-O-Methylguanosine results in apoptotic changes of cells[1][2].

Related Catalog

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Metabolic Disease

References

[1]. B C Persson, et al. The spoU gene of Escherichia coli, the fourth gene of the spoT operon, is essential for tRNA (Gm18) 2'-O-methyltransferase activity. Nucleic Acids Res. 1997 Oct 15;25(20):4093-7.

[2]. T Mori, et al. Isolation and identification of apoptosis inducing nucleosides from CD57(+)HLA-DRbright natural suppressor cell line. Biochem Biophys Res Commun. 1998 Oct 20;251(2):416-22.

Density	2.0±0.1 g/cm3
Boiling Point	711.7ºC at 760 mmHg
Melting Point	218-220ºC
Molecular Formula	C₁₁H₁₅N₅O₅
Molecular Weight	297.267
Flash Point	384.2ºC
Exact Mass	297.107330
PSA	148.51000
LogP	-0.36
Vapour Pressure	2.93E-21mmHg at 25°C
Index of Refraction	1.829
Storage condition	Refrigerator

2'-O-Methylguanosine MSDS(Chinese)

Hazard Codes	Xi
Risk Phrases	36/37/38
Safety Phrases	26-36
HS Code	2934999090

Precursor 9
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