2-Amino-6-chloropurine-9-(2'-O-Methyl)riboside

Modify Date: 2024-02-28 07:47:44

2-Amino-6-chloropurine-9-(2'-O-Methyl)riboside Structure
2-Amino-6-chloropurine-9-(2'-O-Methyl)riboside structure
Common Name 2-Amino-6-chloropurine-9-(2'-O-Methyl)riboside
CAS Number 194034-59-8 Molecular Weight 315.71
Density N/A Boiling Point N/A
Molecular Formula C11H14ClN5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2-Amino-6-chloropurine-9-(2'-O-Methyl)riboside


6-Chloro-9-(2-O-methyl-beta-D-ribofuranosyl)-9H-purin-2-amine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2-amino-6-chloro-9-[2'-O-methyl-β-D-ribofuranosyl]purine
Synonym More Synonyms

  Biological Activity

Description 6-Chloro-9-(2-O-methyl-beta-D-ribofuranosyl)-9H-purin-2-amine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C11H14ClN5O4
Molecular Weight 315.71
Exact Mass 315.07300
PSA 128.54000

 Synonyms

2'-O-methyl-2-amino-6-chloropurine riboside
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