194034-59-8

194034-59-8 structure

Name: 2-Amino-6-chloropurine-9-(2'-O-Methyl)riboside
Chemical Name: 2-amino-6-chloro-9-[2'-O-methyl-β-D-ribofuranosyl]purine
CAS Number: 194034-59-8
Molecular Formula: C₁₁H₁₄ClN₅O₄
Molecular Weight: 315.71
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2016-11-03 03:57:18
Modify Date: 2024-02-28 07:47:44
6-Chloro-9-(2-O-methyl-beta-D-ribofuranosyl)-9H-purin-2-amine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2-amino-6-chloro-9-[2'-O-methyl-β-D-ribofuranosyl]purine
Synonyms	2'-O-methyl-2-amino-6-chloropurine riboside

Description	6-Chloro-9-(2-O-methyl-beta-D-ribofuranosyl)-9H-purin-2-amine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.