KH 176

Modify Date: 2024-01-11 11:14:15

KH 176 Structure
KH 176 structure
Common Name KH 176
CAS Number 2162149-24-6 Molecular Weight 368.902
Density N/A Boiling Point N/A
Molecular Formula C19H29ClN2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of KH 176


KH176 is a chemical entity derivative of Trolox and small molecule ROS-redox modulator, shows potential treatment for mitochondrial disorders; retains brain microstructural coherence in the external capsule in Ndufs4 -/- mice and normalizes the increased lipid peroxidation in this area and the cerebral cortex, significantly improves rotarod and gait performance and reduces the degeneration of retinal ganglion cells in Ndufs4 -/- mice. Other Indication Phase 2 Clinical

 Names

Name KH 176

 KH 176 Biological Activity

Description KH176 is a chemical entity derivative of Trolox and small molecule ROS-redox modulator, shows potential treatment for mitochondrial disorders; retains brain microstructural coherence in the external capsule in Ndufs4 -/- mice and normalizes the increased lipid peroxidation in this area and the cerebral cortex, significantly improves rotarod and gait performance and reduces the degeneration of retinal ganglion cells in Ndufs4 -/- mice. Other Indication Phase 2 Clinical
References References 1. de Haas R, et al. Sci Rep. 2017 Sep 15;7(1):11733. 2. Koene S, et al. Orphanet J Rare Dis. 2017 Oct 16;12(1):163. View Related Products by Target Other Targets Other Indication

 Chemical & Physical Properties

Molecular Formula C19H29ClN2O3
Molecular Weight 368.902
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