2162149-24-6
2162149-24-6 structure
- Name: KH 176
- Chemical Name: KH 176
- CAS Number: 2162149-24-6
- Molecular Formula: C19H29ClN2O3
- Molecular Weight: 368.902
- Catalog: Research Areas Metabolic Disease
- Create Date: 2020-01-20 18:46:57
- Modify Date: 2024-01-11 11:14:15
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KH176 is a chemical entity derivative of Trolox and small molecule ROS-redox modulator, shows potential treatment for mitochondrial disorders; retains brain microstructural coherence in the external capsule in Ndufs4 -/- mice and normalizes the increased lipid peroxidation in this area and the cerebral cortex, significantly improves rotarod and gait performance and reduces the degeneration of retinal ganglion cells in Ndufs4 -/- mice. Other Indication Phase 2 Clinical
| Name | KH 176 |
|---|
| Description | KH176 is a chemical entity derivative of Trolox and small molecule ROS-redox modulator, shows potential treatment for mitochondrial disorders; retains brain microstructural coherence in the external capsule in Ndufs4 -/- mice and normalizes the increased lipid peroxidation in this area and the cerebral cortex, significantly improves rotarod and gait performance and reduces the degeneration of retinal ganglion cells in Ndufs4 -/- mice. Other Indication Phase 2 Clinical |
|---|---|
| References | References 1. de Haas R, et al. Sci Rep. 2017 Sep 15;7(1):11733. 2. Koene S, et al. Orphanet J Rare Dis. 2017 Oct 16;12(1):163. View Related Products by Target Other Targets Other Indication |
| Molecular Formula | C19H29ClN2O3 |
|---|---|
| Molecular Weight | 368.902 |