2162149-24-6

2162149-24-6 structure

Name: KH 176
Chemical Name: KH 176
CAS Number: 2162149-24-6
Molecular Formula: C₁₉H₂₉ClN₂O₃
Molecular Weight: 368.902
Catalog: Research Areas Metabolic Disease
Create Date: 2020-01-20 18:46:57
Modify Date: 2024-01-11 11:14:15
KH176 is a chemical entity derivative of Trolox and small molecule ROS-redox modulator, shows potential treatment for mitochondrial disorders; retains brain microstructural coherence in the external capsule in Ndufs4 -/- mice and normalizes the increased lipid peroxidation in this area and the cerebral cortex, significantly improves rotarod and gait performance and reduces the degeneration of retinal ganglion cells in Ndufs4 -/- mice. Other Indication Phase 2 Clinical

Name	KH 176

Description	KH176 is a chemical entity derivative of Trolox and small molecule ROS-redox modulator, shows potential treatment for mitochondrial disorders; retains brain microstructural coherence in the external capsule in Ndufs4 -/- mice and normalizes the increased lipid peroxidation in this area and the cerebral cortex, significantly improves rotarod and gait performance and reduces the degeneration of retinal ganglion cells in Ndufs4 -/- mice. Other Indication Phase 2 Clinical
References	References 1. de Haas R, et al. Sci Rep. 2017 Sep 15;7(1):11733. 2. Koene S, et al. Orphanet J Rare Dis. 2017 Oct 16;12(1):163. View Related Products by Target Other Targets Other Indication

Molecular Formula	C₁₉H₂₉ClN₂O₃
Molecular Weight	368.902