Ac-Ile-Glu-Pro-Asp-AMC

Modify Date: 2024-01-09 06:12:46

Ac-Ile-Glu-Pro-Asp-AMC Structure
Ac-Ile-Glu-Pro-Asp-AMC structure
 Common Name Ac-Ile-Glu-Pro-Asp-AMC
CAS Number 216757-33-4 Molecular Weight 671.69
Density 1.4±0.1 g/cm3 Boiling Point 1116.0±65.0 °C at 760 mmHg
Molecular Formula C32H41N5O11 Melting Point N/A
MSDS Chinese USA Flash Point 628.7±34.3 °C

 Use of Ac-Ile-Glu-Pro-Asp-AMC


Ac-IEPD-AMC is a fluorogenic substrate for the determination of protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal[1].

 Names

Name ac-iepd-amc
Synonym More Synonyms

 Ac-Ile-Glu-Pro-Asp-AMC Biological Activity

Description Ac-IEPD-AMC is a fluorogenic substrate for the determination of protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal[1].
Related Catalog
References

[1]. Scott JI, et, al. A Functional Chemiluminescent Probe for in Vivo Imaging of Natural Killer Cell Activity Against Tumours. Angew Chem Int Ed Engl. 2021 Mar 8;60(11):5699-5703.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 1116.0±65.0 °C at 760 mmHg
Molecular Formula C32H41N5O11
Molecular Weight 671.69
Flash Point 628.7±34.3 °C
Exact Mass 671.280273
PSA 241.52000
LogP 1.98
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.593

 Safety Information

WGK Germany 3

 Synonyms

ac-ile-glu-pro-asp-7-amino-4-methylcoumarin
L-α-Asparagine, N-acetyl-L-isoleucyl-L-α-glutamyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
granzyme b substrate ix,fluorogenic
ac-ile-glu-pro-asp-amc
N-Acetyl-L-isoleucyl-L-α-glutamyl-L-prolyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-α-asparagine
n-acetyl-ile-glu-pro-asp-7-amido-4-methylcoumarin
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