Ac-Ile-Glu-Thr-Asp-pNA structure
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Common Name | Ac-Ile-Glu-Thr-Asp-pNA | ||
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CAS Number | 219138-21-3 | Molecular Weight | 638.624 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | 1140.8±65.0 °C at 760 mmHg | |
Molecular Formula | C27H38N6O12 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 643.7±34.3 °C |
Use of Ac-Ile-Glu-Thr-Asp-pNAAc-Ile-Glu-Thr-Asp-pNA is a substrate for caspase-8. Caspase-8 binds to and cleaves the Ile-Glu-Thr-Asp (IETD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity[1]. |
Name | ac-ietd-pna |
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Synonym | More Synonyms |
Description | Ac-Ile-Glu-Thr-Asp-pNA is a substrate for caspase-8. Caspase-8 binds to and cleaves the Ile-Glu-Thr-Asp (IETD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity[1]. |
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Related Catalog | |
References |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 1140.8±65.0 °C at 760 mmHg |
Molecular Formula | C27H38N6O12 |
Molecular Weight | 638.624 |
Flash Point | 643.7±34.3 °C |
Exact Mass | 638.254761 |
PSA | 286.15000 |
LogP | 1.27 |
Vapour Pressure | 0.0±0.3 mmHg at 25°C |
Index of Refraction | 1.583 |
ac-ietd-amc |
z-ala-ala-asp-afc |
N-Acetyl-L-isoleucyl-L-α-glutamyl-L-threonyl-N-(4-nitrophenyl)-L-α-asparagine |
ac-ile-glu-thr-asp-mca |
ac-ietd-mca |
L-α-Asparagine, N-acetyl-L-isoleucyl-L-α-glutamyl-L-threonyl-N-(4-nitrophenyl)- |
pase-8 substrate |
pase-8 substrate i |
ac-ile-glu-thr-asp-amc |
ax-ietd-amc |
granzyme b substrate |