AT-007

Modify Date: 2024-01-09 11:26:18

AT-007 Structure
AT-007 structure
Common Name AT-007
CAS Number 2170729-29-8 Molecular Weight 425.40
Density N/A Boiling Point N/A
Molecular Formula C17H10F3N3O3S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AT-007


AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase inhibitor for treatment of Galactosemia with an IC50 value of 100 pM[1][2].

 Names

Name AT-007

 AT-007 Biological Activity

Description AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase inhibitor for treatment of Galactosemia with an IC50 value of 100 pM[1][2].
Target

IC50: 100 pM (Aldose Reductase)[2]

References

[1]. Maeve Conneighton, et al. Applied Therapeutics Announces Initiation of Phase 1/2 Study of AT-007 in Galactosemia.

[2]. UNITED STATES SECURITIES AND EXCHANGE COMMISSION. APPLIED THERAPEUTICS, INC.

 Chemical & Physical Properties

Molecular Formula C17H10F3N3O3S2
Molecular Weight 425.40
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Price: ¥3276/10 mM * 1 mL in DMSO

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