L-threonolactone

Modify Date: 2024-02-01 17:10:11

L-threonolactone Structure
L-threonolactone structure
Common Name L-threonolactone
CAS Number 21730-93-8 Molecular Weight 118.09
Density 0.99g/cm3 Boiling Point 277.8ºC at 760mmHg
Molecular Formula C4H6O4 Melting Point N/A
MSDS USA Flash Point 101.3ºC

 Use of L-threonolactone


L-Threonolactone ((3R,4S)-3,4-Dihydroxyoxolan-2-one) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name L-threonolactone
Synonym More Synonyms

 L-threonolactone Biological Activity

Description L-Threonolactone ((3R,4S)-3,4-Dihydroxyoxolan-2-one) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 0.99g/cm3
Boiling Point 277.8ºC at 760mmHg
Molecular Formula C4H6O4
Molecular Weight 118.09
Flash Point 101.3ºC
Exact Mass 118.02700
PSA 66.76000
Vapour Pressure 0.00443mmHg at 25°C
Index of Refraction 1.437

 Safety Information

RIDADR NONH for all modes of transport
HS Code 2932209090

 Precursor & DownStream

Precursor  0

DownStream  1

 Customs

HS Code 2932209090
Summary 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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 Synonyms

2,3-dihydroxydihydrofuran-1-one
Threonolactone
di-TMS-Threono-1,4-lactone
(3R,4S)-3,4-Dihydroxydihydrofuran-2(3H)-one
L-threonic acid-4-lactone
threonic acid-1,4-lactone
L-treono-1,4-lactone
L-Threonic acid-1,4-lactone
(3R,4S)-3,4-dihydroxyoxolan-2-one
Bis-TMS-Threono-1,4-lactone
L-Threonsaeure-4-lacton
(3R,4S)-3,4-dihydroxy-dihydrofuran-2-one