Bcl-2/Bcl-xl inhibitor 1
Modify Date: 2024-01-06 22:22:32
Bcl-2/Bcl-xl inhibitor 1 structure
|
Common Name | Bcl-2/Bcl-xl inhibitor 1 | ||
|---|---|---|---|---|
| CAS Number | 2180923-05-9 | Molecular Weight | 882.42 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C45H48ClN7O8S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Bcl-2/Bcl-xl inhibitor 1Bcl-2/Bcl-xl inhibitor 1 (compound 6) is a dual Bcl-2 and Bcl-xl inhibitor with anti-tumor activity, extracted from patent WO2018027097A1. Bcl-2/Bcl-xl inhibitor 1 exhibits IC50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl, respectively[1]. |
| Name | Bcl-2/Bcl-xl inhibitor 1 |
|---|
| Description | Bcl-2/Bcl-xl inhibitor 1 (compound 6) is a dual Bcl-2 and Bcl-xl inhibitor with anti-tumor activity, extracted from patent WO2018027097A1. Bcl-2/Bcl-xl inhibitor 1 exhibits IC50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl, respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
Bcl-2:2 nM (IC50) Bcl-xL:5.9 nM (IC50) |
| In Vitro | Bcl-2/Bcl-xl inhibitor 1 (compound 6) exhibits IC50 values of 5.5 nM and 6.4 nM in Bcl-2 dependent RS4;11 cells and Bcl-xl dependent Molm13 cells[1]. |
| References |
| Molecular Formula | C45H48ClN7O8S |
|---|---|
| Molecular Weight | 882.42 |
| Storage condition | 2-8°C |