N-(acid-PEG3)-N-bis(PEG3-amine)

Modify Date: 2024-01-09 22:04:46

N-(acid-PEG3)-N-bis(PEG3-amine) Structure
N-(acid-PEG3)-N-bis(PEG3-amine) structure
Common Name N-(acid-PEG3)-N-bis(PEG3-amine)
CAS Number 2183440-35-7 Molecular Weight 571.70
Density N/A Boiling Point N/A
Molecular Formula C25H53N3O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-(acid-PEG3)-N-bis(PEG3-amine)


N-(PEG3-acid)-N-bis(PEG3-amine) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-(PEG3-acid)-N-bis(PEG3-amine)
Synonym More Synonyms

 N-(acid-PEG3)-N-bis(PEG3-amine) Biological Activity

Description N-(PEG3-acid)-N-bis(PEG3-amine) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C25H53N3O11
Molecular Weight 571.70

 Synonyms

MFCD31580144