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2183440-35-7

2183440-35-7 structure
2183440-35-7 structure
  • Name: N-(acid-PEG3)-N-bis(PEG3-amine)
  • Chemical Name: N-(PEG3-acid)-N-bis(PEG3-amine)
  • CAS Number: 2183440-35-7
  • Molecular Formula: C25H53N3O11
  • Molecular Weight: 571.70
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 08:23:36
  • Modify Date: 2024-01-09 22:04:46
  • N-(PEG3-acid)-N-bis(PEG3-amine) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-(PEG3-acid)-N-bis(PEG3-amine)
Synonyms MFCD31580144
Description N-(PEG3-acid)-N-bis(PEG3-amine) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C25H53N3O11
Molecular Weight 571.70