ShK-Dap22 structure
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Common Name | ShK-Dap22 | ||
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CAS Number | 220384-25-8 | Molecular Weight | N/A | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C166H268N54O48S7 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of ShK-Dap22ShK-Dap22 is a potent Kv1.3-specific immunosuppressive Polypeptide. ShK-Dap22 is a selective Kv1.3 channel blocker with IC50s of 23 pM, 1.8 nM, 10.5 nM, 37 nM, and 39 nM for mKv1.3, mKv1.1, hKv1.6, mKv1.4, and rKv1.2 channels, respectively[1]. |
Name | (Dap22)-Stichodactyla helianthus Neurotoxin (ShK) |
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Description | ShK-Dap22 is a potent Kv1.3-specific immunosuppressive Polypeptide. ShK-Dap22 is a selective Kv1.3 channel blocker with IC50s of 23 pM, 1.8 nM, 10.5 nM, 37 nM, and 39 nM for mKv1.3, mKv1.1, hKv1.6, mKv1.4, and rKv1.2 channels, respectively[1]. |
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Related Catalog | |
In Vitro | ShK-Dap22 suppresses T cell activation in vitro. ShK-Dap22, at subnanomolar concentrations, suppresses anti-CD3 induced human T-lymphocyte [3H]thymidine incorporation in vitro[1]. |
References |
Molecular Formula | C166H268N54O48S7 |
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