ATG7-IN-2

Modify Date: 2024-01-28 13:12:30

ATG7-IN-2 Structure
ATG7-IN-2 structure
Common Name ATG7-IN-2
CAS Number 2226227-75-2 Molecular Weight 376.35
Density N/A Boiling Point N/A
Molecular Formula C11H16N6O7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ATG7-IN-2


ATG7-IN-2 (compound 1) is a potent ATG7 inhibitor, with an IC50 of 0.089 μM. ATG7-IN-2 inhibits autophagy marker LC3B[1].

 Names

Name ATG7-IN-2

 ATG7-IN-2 Biological Activity

Description ATG7-IN-2 (compound 1) is a potent ATG7 inhibitor, with an IC50 of 0.089 μM. ATG7-IN-2 inhibits autophagy marker LC3B[1].
Related Catalog
Target

IC50: 0.089 ± 0.036 μM (ATG7), 0.335 ± 0.049 μM (Thioester), 2.6 μM (LC3B)[1]

References

[1]. Huang SC, et al. Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors. Bioorg Med Chem. 2020 Oct 1;28(19):115681.

 Chemical & Physical Properties

Molecular Formula C11H16N6O7S
Molecular Weight 376.35