BI-1408

Modify Date: 2024-01-13 23:03:41

BI-1408 Structure
BI-1408 structure
Common Name BI-1408
CAS Number 2231075-94-6 Molecular Weight 390.46
Density N/A Boiling Point N/A
Molecular Formula C22H23FN6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BI-1408


BI-1408 is a potent γ secretase modulator with an IC50 of 0.04 μM for Aβ42[1].

 Names

Name BI-1408

 BI-1408 Biological Activity

Description BI-1408 is a potent γ secretase modulator with an IC50 of 0.04 μM for Aβ42[1].
Related Catalog
Target

IC50: 40 nM (Aβ42)[1]

References

[1]. Gerlach K, et al. Discovery of tetrahydroindazoles as a novel class of potent and in vivo efficacious gamma secretase modulators. Bioorg Med Chem. 2018 Jul 23;26(12):3227-3241.

 Chemical & Physical Properties

Molecular Formula C22H23FN6
Molecular Weight 390.46