TK4b

Modify Date: 2024-01-06 21:26:35

TK4b structure	Common Name	TK4b
	CAS Number	2232890-81-0	Molecular Weight	334.41
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₂N₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TK4b

TK4b is a Janus kinase (JAK) inhibitor with the IC50 values of 19.40 nM and 18.42 nM for JAK2 and JAK3, respectively. TK4b can be used in lymphoid-derived diseases and leukemia cancer research[1].

Name	TK4b

Description	TK4b is a Janus kinase (JAK) inhibitor with the IC50 values of 19.40 nM and 18.42 nM for JAK2 and JAK3, respectively. TK4b can be used in lymphoid-derived diseases and leukemia cancer research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK
Target	JAK2:19.40 nM (IC50) JAK3:18.42 nM (IC50)
References	[1]. Kamonpan Sanachai, et al. Pharmacophore-Based Virtual Screening and Experimental Validation of Pyrazolone-Derived Inhibitors toward Janus Kinases. ACS Omega 2022.

Molecular Formula	C₂₁H₂₂N₂O₂
Molecular Weight	334.41