BCL6 PROTAC 1
Modify Date: 2024-01-12 09:22:28
BCL6 PROTAC 1 structure
|
Common Name | BCL6 PROTAC 1 | ||
|---|---|---|---|---|
| CAS Number | 2257479-54-0 | Molecular Weight | 946.40 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C45H52ClN9O12 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BCL6 PROTAC 1BCL6 PROTAC 1 is a selective B-cell lymphoma 6 (BCL6) PROTAC. BCL6 PROTAC 1 inhibits BCL6 cell reporter with an IC50 value of 8.8 µM. BCL6 PROTAC 1 significantly degrades BCL6 in diffuse large B-cell lymphoma (DLBCL) cell lines. BCL6 PROTAC 1 can be used in tumor related research[1]. |
| Name | BCL6 PROTAC 1 |
|---|
| Description | BCL6 PROTAC 1 is a selective B-cell lymphoma 6 (BCL6) PROTAC. BCL6 PROTAC 1 inhibits BCL6 cell reporter with an IC50 value of 8.8 µM. BCL6 PROTAC 1 significantly degrades BCL6 in diffuse large B-cell lymphoma (DLBCL) cell lines. BCL6 PROTAC 1 can be used in tumor related research[1]. |
|---|---|
| Related Catalog | |
| Target |
B-cell lymphoma 6, BCL6[1] |
| In Vitro | BCL6 PROTAC 1 (Compound 15) (0.0001-10 µM；1-72 h) 在 OCI-Ly1 细胞中，以剂量依赖性方式降解 B 细胞淋巴瘤 6 (BCL6)[1]。 Cell Viability Assay[1] Cell Line: OCI-Ly1 cells. Concentration: 1 µM. Incubation Time: 16 d. Result: Had no effect on cell viability. Western Blot Analysis[1] Cell Line: OCI-Ly1 cells. Concentration: 0.0001, 0.001, 0.01, 0.1, 0.2, 1, 3, 5 and 10 µM. Incubation Time: 1, 2, 4, 6, 8, 10, 24, 48, 72 h. Result: Degraded BCL6. |
| References |
| Molecular Formula | C45H52ClN9O12 |
|---|---|
| Molecular Weight | 946.40 |