CC-92480
Modify Date: 2024-01-03 15:31:05
CC-92480 structure
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Common Name | CC-92480 | ||
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| CAS Number | 2259648-80-9 | Molecular Weight | 567.61 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C32H30FN5O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CC-92480CC-92480 is a cereblon E3 ubiquitin ligase modulating drug (CELMoD). CC-92480 shows high affinity to cereblon, resulting in potent antimyeloma activity[1]. |
| Name | CC-92480 |
|---|---|
| Synonym | More Synonyms |
| Description | CC-92480 is a cereblon E3 ubiquitin ligase modulating drug (CELMoD). CC-92480 shows high affinity to cereblon, resulting in potent antimyeloma activity[1]. |
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| Related Catalog | |
| In Vitro | CC-92480 is the second cereblon modulator. CC-92480-induced loss of Aiolos and Ikaros in cultures of PBMCs resulted in the activation of T cells and increased production of IL-2 and interferon γ. CC-92480 is effective in lenalidomide, pomalidomide, and CC-220-resistant cell lines. It exerts single-agent induction of apoptosis and exhibits remarkable synergy with dexamethasone[1]. |
| References |
| Molecular Formula | C32H30FN5O4 |
|---|---|
| Molecular Weight | 567.61 |
| Hazard Codes | Xi |
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| MFCD32263041 |