2'-Deoxy-N4-methylcytidine

Modify Date: 2024-01-09 16:26:51

2'-Deoxy-N4-methylcytidine Structure
2'-Deoxy-N4-methylcytidine structure
Common Name 2'-Deoxy-N4-methylcytidine
CAS Number 22882-02-6 Molecular Weight 241.24
Density 1.56g/cm3 Boiling Point 460.5ºC at 760mmHg
Molecular Formula C10H15N3O4 Melting Point N/A
MSDS N/A Flash Point 232.3ºC

 Use of 2'-Deoxy-N4-methylcytidine


2’-Deoxy-N4-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(methylamino)pyrimidin-2-one
Synonym More Synonyms

 2'-Deoxy-N4-methylcytidine Biological Activity

Description 2’-Deoxy-N4-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.56g/cm3
Boiling Point 460.5ºC at 760mmHg
Molecular Formula C10H15N3O4
Molecular Weight 241.24
Flash Point 232.3ºC
Exact Mass 241.10600
PSA 100.10000
Vapour Pressure 2.04E-10mmHg at 25°C
Index of Refraction 1.665
Storage condition 2-8℃

 Synthetic Route

 Synonyms

N(3)-Methyl-2'-deoxycytidine
2'-Deoxy-N(3)-methylcytidine
N4-methyl-2'-deoxycytidine
m3dC
2'-deoxy-N4-methyl-cytidine
Cytidine,2'-deoxy-N-methyl
2'-deoxy-4-N-methylcytidine
N-methyl-2'-deoxycytidine
2'-Deoxy-N4-methylcytidine
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