2’,3’-Bis(O-t-butyldimethylsilyl)-2-thiouridine

Modify Date: 2024-01-11 22:44:40

2’,3’-Bis(O-t-butyldimethylsilyl)-2-thiouridine Structure
2’,3’-Bis(O-t-butyldimethylsilyl)-2-thiouridine structure
Common Name 2’,3’-Bis(O-t-butyldimethylsilyl)-2-thiouridine
CAS Number 2305415-97-6 Molecular Weight 488.79
Density N/A Boiling Point N/A
Molecular Formula C21H40N2O5SSi2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2’,3’-Bis(O-t-butyldimethylsilyl)-2-thiouridine


2’,3’-Bis(O-t-butyldimethylsilyl)-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2’,3’-Bis(O-t-butyldimethylsilyl)-2-thiouridine

  Biological Activity

Description 2’,3’-Bis(O-t-butyldimethylsilyl)-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C21H40N2O5SSi2
Molecular Weight 488.79